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Poverty is an important factor for causing unipolar depression in any form and at any age. While antidepressants raise serotonin levels within hours, it takes weeks before medication kicks in to relieve depression. Chronic inability to sleep could also cause depression. If you stop medication before your depression has fully improved, it's much more likely to return. Low folate levels could trigger depression and produce poor response to antidepressant medications. If any of your current medications.

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